You've got hardware that go far beyond the minimum requirements, that, perhaps things are just running at "too new" of settings/hardware. Have you tried compatibility mode? I have only one Win 10 machine and I haven't attempted running EQ from it, thus a shot in the dark here.
Also, look to see how many cores EQ is using. You may need to set affinity for it to utilize more than one core. Beyond those things I'm out of ideas, as again I've yet to run EQ on the Win10 machine.
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