Just to be clear, if you are trying to run from a fully installed version of EQ and have run the patcher its not going to work. Since your EQ seems to be installed in Program Files or another system controlled area, I thought I would mention it.
You can create a directory off the root, like c:\Games\Everquest and move it there. Another option is to move it to the c:\Users\Public. You should be able to edit your file from either of those locations. Alternatively you can run Notepad as administrator, just Right Click it, do Run as Administrator, then open the file using the File menu. HTH
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