Did you follow this guide to get it working? You need to follow it exactly:
http://www.eqemulator.net/wiki/wikka...akka=PlayGuide
Make sure you are using the shortcut and NOT clicking any exe files. You have to have the patchme statement of the eqgame.exe will error and tell you to run everquest.exe. Get that far and let us know if you need help with further issues.
Also, make SURE you are running a legal copy of Everquest Titanium pack. Anything other than that, or any illegal copies will not work and will not be supported on these forums.