I enjoy Profusion - it has custom progression and loot. As an example, your first task for progression starts immediately and requires you to kill three named mobs in Crushbone. The reward is your Epic 1.0.
Second tier progression is unrest, third L Guk and I think by this tier I was seeing Fungi tunics drop.
Very solo friendly whether or not you want to use MQ. Come check out more in the discord,
https://discord.gg/pmJPB4Df